Is kēpos GLP-1 friendly?Updated a month ago

GLP-1 receptor agonists, such as semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro), have become increasingly common tools for managing weight, insulin resistance, and metabolic syndrome. While these medications are effective at regulating appetite and improving glycemic control, they also place significant stress on the gut microbiome and digestive system. This is where kēpos offers uniquely supportive benefits.

Many individuals on GLP-1 therapies experience gastrointestinal side effects: nausea, bloating, constipation, and reduced microbial diversity. These issues can disrupt nutrient absorption, gut-brain signaling, and long-term metabolic stability. kēpos was designed to restore and fortify the gut ecosystem at a level that complements these medications without interference.

The Human Milk Oligosaccharides (HMOs) in kēpos serve as precision prebiotics, selectively feeding foundational microbial species like Bifidobacterium infantis and Akkermansia muciniphila—both of which are associated with improved metabolic control, reduced inflammation, and enhanced gut barrier integrity. By supporting these bacteria, kēpos helps maintain the microbial diversity and mucosal health often diminished on GLP-1 drugs or during caloric restriction.

Additionally, the human-identical lactoferrin (hmLF) in kēpos helps regulate iron metabolism and immune function while directly supporting the gut lining. This is critical in the context of GLP-1 use, where slowed gastric emptying and altered digestive motility can increase microbial imbalances and gut permeability. Lactoferrin also has known anti-inflammatory properties, helping to counteract the low-grade inflammation that can accompany rapid weight loss or metabolic shifts.

While kēpos is not a replacement for GLP-1 medications, it is designed to fill in the biological gaps they leave behind, supporting microbiome resilience, immune balance, and digestive comfort. For those using GLP-1s as part of a long-term metabolic strategy, kēpos offers a way to stay rooted in gut health while pursuing powerful therapeutic outcomes.

As always, consult your healthcare provider before combining supplements with prescription therapies.